Ibn Othman Mosque is located in the Shujaiya neighborhood, east of Gaza City. It is the second largest historical mosque after the Great Omar Mosque. The mosque is named after Shihab al-Din Ibn Othman, one of the religious scholars of Gaza. Its construction dates back to the year 1400 AD. The western arcade of the mosque contains the tomb of Prince Yaljha, the ruler of Gaza during the Mamluk Sultan Barquq's reign, who passed away in 1446 AD.

The residents of the Shujaiya neighborhood refer to this mosque as "The Grand Mosque" due to its large size and its central location in the main market of the neighborhood, which has had a significant impact on their lives throughout the historical periods since its establishment more than 600 years ago.

The mosque, which follows Mamluk architectural style, has an area of 2000 square meters, of which 400 square meters are occupied by its main courtyard. It has two gates that open onto the Shujaiya market.

Israeli occupation aircraft launched several large missiles at Ibn Othman Mosque, located in the heart of the Shujaiya neighborhood, resulting in its complete destruction.